Does getting ‘expensive’ drug affect how much patient benefits?
Since I talk about the placebo effect from time to time I figure this might be interesting to my reader(s)…
For the study, 12 people with Parkinson’s disease were told that they would receive shots of two formulations of the same drug, with the second shot given after the first shot wore off. They were told that the formulations were believed to be of similar effectiveness, but that they differed in manufacturing cost–$100 per dose versus $1,500 per dose. Participants were told that the study was intended to prove that the drugs, while priced differently, were equally effective.
In reality, the participants received only a saline solution for both injections, but were told they were receiving either the “cheap” or “expensive” drug first. Before and after each shot, participants took several tests to measure their motor skills and also had brain scans to measure brain activity.
When people received the “expensive” drug first, their motor skills improved by 28 percent compared to when they received the “cheap” drug. On one test of motor skills, people’s scores improved by seven points when taking the “expensive” drug first, but improved by only three points when taking the “cheap” drug.