All genes aren’t indispensable
Even with about 20 that are utterly inactivated, individuals can do just fine
http://www.sciencenews.org/view/generic/id/338526/title/All_genes_arent_indispensable
I have talked a time or twain about DNA before, how the relatively simple theory I learned back in school (more than 20 years ago! man am I getting old!) turns out to be a very crude picture. Unlike Newtonian physics that explain everything except at the very small (where quantum mechanics takes over) or very large (where Einsteinian physics takes over (but note that there is, as yet, no theory that explains everything!)), the earlier DNA theory I learned was really just the bare brush strokes of how things are turning out to work. This article provides even more grist for the mill in that regard, perfectly healthy people are missing genes heretofore considered necessary for health.